Unidad de Biología Celular y Virología
La Unidad de Biología Celular y Virología realiza investigación en plantas medicinales como fuentes de nuevos fármacos. Las actividades estudiadas actualmente son las siguientes: actividad antitumoral, actividad antibacteriana, actividad antidiarreica y enfermedades mentales.
La importancia de esta unidad radica en la posibilidad de descubrir nuevos fármacos a partir de la medicina tradicional y con ello darle valor agregado a nuestros recursos naturales.
- Dr. Abraham Vaisberg Wolach
Coordinador - Ramiro Condori Salas
Tesista
- Unidad de Neurobiología Molecular, LID
- Unidad de Bioquímica de Membranas, LID
- Unidad de Investigación de Productos Naturales, LID.
- Unidad de Parasitología Celular, LID
- Unidad de Microbiología del LID
- Universidad de Louisville, Kentucky
- Universidad Nacional Mayor de San Marcos
- Universidad de Carolina del Norte. Chapel Hill
- Universidad de Lima
- Unidad de Control de calidad, LID
Algunos proyectos de investigación
Oprhan GPCR ligands from ethnobotanical sources as novel drugs for mental disorders
CONCLUIDO
Screening marine microalgae and terrestrial bacteria in search of novel compounds of potential and other industrial values
CONCLUIDO
Isolation and identification of CXCR4 and CXCR7 agonists from traditional phytopharmaceuticals as potential novel drugs for mental disorders
EN EJECUCIÓN
Algunas publicaciones
+ Novel Thiosemicarbazone Derivatives from Furan-2-Carbaldehyde: Synthesis, Characterization, Crystal Structures, and Antibacterial, Antifungal, Antioxidant, and Antitumor Activities
DOI: 10.1155/2023/5413236
+ Non-affective psychosis in traditional Andean culture
+ Synthesis, Spectroscopic Characterization, Structural Studies, and In Vitro Antitumor Activities of Pyridine-3-carbaldehyde Thiosemicarbazone Derivatives
DOI: 10.1155/2020/2960165
+ Cytotoxic and Anti-Methicillin Resistant Staphilococcus aureus Activities of Extracts from Streptomyces spp. Isolated from Mineral Ores
+ Screening the Pathogen Box for Identification of New Chemical Agents with Anti-Fasciola hepatica Activity
DOI: 10.1128/aac.02373-18
+ Plagiochiline A Inhibits Cytokinetic Abscission and Induces Cell Death
Producción tecnológica
- Synthesis of stable organogold compounds and methods of use thereof (WO2010062846)
Disclosed herein are novel gold containing compounds and methods of synthesis and use thereof. The novel compounds are very stable. The stability of the compounds allows for their use in methods of treating cancer cells. Disclosed herein are examples of the use of the compounds to inhibit growth of cancer cell lines. The utility of the compounds disclosed herein is a method of treating cancer cells in which a therapeutically effective amount of a compound is administered. - Compounds, Compositions, Pharmaceutical Compositions, and Methods of Use (PCT/WO2013/074905)
Certain embodiments of the invention include compositions comprising a compound of Formula (I), and salts, isomers, and derivatives thereof. Pharmaceutical compositions of Some embodiments of the present invention comprise a compound of Formula (I), and salts, isomers, and derivatives thereof. Other embodiments of this invention include meth ods for treating disease (e.g., cancer) and methods for administering a compound of Formula (I), and salts, iso mers, and derivatives thereof. - Compounds related to chalcones and benzothienopyrimidines, their synthesis, and uses to treat diseases (US Patent No. US9,061,984 B2)
Embodiments of the present invention provide compounds (such as Formula (I) compounds, Formula (II) compounds, and various embodiments thereof). Compositions comprising those compounds are also provided. Methods for their preparation are included. Also, uses of the compounds are included, such as administering and treating diseases (e.g., cancer and infections).
Equipos
- Baker Laminar Flow Hood, Modelo EdgeGard
- Baker Vertical Flow Hood, Modelos SterilGard y SterilGard III Advance
- Incubadoras de CO2 Forma Scientific
- Contador de células Coulter Electronics
- Balanza analítica Mettler analytical
- Centrifuga Sorval T6000D
- Microscopio Invertido de contraste de fases con sistema de fotografía digital Nikon Eclipse Ti
- Microscopio invertido de contraste de fases Leitz Diavert con sistema de fotografía
- Microscopio invertido de contraste de fases Bausch and Lomb
- Microscopio Leitz Ortholux
- Microscopio estereoscopico Fisher Scientific
- Microcentrifuga Eppendorf
- Autoclave Harvey SterileMax
- Hornos para esterilización
- Evaporadores rotativos Buchler
- Lofilizadora Labconco de 12L de capacidad
- Sistema Thermolyne Locator 8 para criopreservación
- Congeladora de – 85°C Forma Scientific
- Centrifuga Refrigerada Sorval Biofuge Primo R
- Zeiss laser scanning confocal microscope
- A Dionex Ultimate 3000 UHPLC
- Q Exactive Hybrid Quadrupole-Orbitrap Mass Spectrometer
- Flow Cytometer (BD FACS Canto II)
Premios
Premio Southern-Perú y Medalla Cristobal de Losada y Puga a la Creatividad Humana
Pontificia Universidad Católica del Perú
2019
Distinción Santiago Antúnez de Mayolo Gomero por investigación en ciencias
Consejo Nacional de Ciencia Tecnología e Innovación Tecnológica del Perú
2014
Epónimo de los Laboratorios de Investigación y Desarrollo
Universidad Peruana Cayetano Heredia
2010
Designado Académico de la Academia de Ciencias de América Latina
Academia de Ciencias de América Latina
2004
Nombrado miembro honorario del Colegio de Biólogos del Perú
Colegio de Biólogos del Perú
2000
Miembro de la Orden Cayetano Heredia en el Grado de Gran Oficial
Universidad Peruana Cayetano Heredia
1999